Cape Girardeau, Missouri
Since 1980

Advanced Pest Control Systems, Inc. is the firm to call when it's time to get rid of annoying pest problems. We offer residential and commercial pest control, termite control, weed control, rodent control and the Sentricon Colony Elimination System.

Advanced Pest Control has been keeping homes bug free for more than 30 years in Missouri and Illinois. Our expert exterminators can help you get rid of bed bugs, termites, spiders, ants, cockroaches, mice and many other pests. Whether you need pest control in Cape Girardeau, Kennett, St. Louis, Southern Illinois or anywhere in between, contact Advanced Pest Control today.

Make an appointment
  • Call us at 573-334-4215
  • Tell us the type of problem and where it’s located
  • We will provide info to help prepare for our visit
  • Date and time will be determined
  • Or click the link below and complete the form

Residential and Commercial Pest Control Services

Residential Services

At Advanced Pest Control Systems it is our goal to implement pest control in your home to the best of our ability.  When coming to your home we will thoroughly inspect for any pest infestation.  After the initial inspection, we will complete the following tasks:

  • Spray around baseboards in every room and floor of your home
  • Spray six to eight feet from the foundation out into your yard
  • Fog attic with Actisol machine (per request)
  • Set out mouse/rat bait (per request)
  • Set out gel bait around counter tops and sinks for roaches and/or ants (if required)
Commercial Services

At Advanced Pest Control Systems, we understand the importance of having pest control in your place of business. When coming to your place of business we will thoroughly inspect for any pest infestation.  After the initial inspection, we will complete the following tasks:

  • Spray around baseboards in all offices, kitchen areas (underneath sinks), restrooms, pantries, closets, hallways and any other rooms that are requested to be sprayed
  • Spray six to eight feet from the foundation out for exterior spraying
  • Set out mouse/rat bait (per request)
[Sentricon logo]
Sentricon Termite Colony Elimination System

What is Sentricon Termite Colony Elimination System?

With its patented active ingredient, proven colony elimination record and successful installation around the perimeter of more than 2 million properties, the Sentricon Termite Colony Elimination System is by far the leader in termite baiting technology.

Why do homeowners prefer the Sentricon Termite Colony Elimination System?

As a homeowner, you have many options for treating subterranean termites. Unfortunately, they don't all protect your home. In fact, there is a wide range of effectiveness among termite baits.

  • Proven termite colony elimination, as shown by 30 independent university studies, 45 published scientific articles and long-term real-life success.
  • Sentricon is only provided by companies specially qualified, trained and authorized by Dow AgroSciences, to promote quality service and continue system integrity.
  • Proven protection of more than 2 million structures, including national treasures such as the White House,  Statue of Liberty, the Alamo and Independence Hall.
  • Protection that's easy on the environment, only using a few grams of active ingredient to eliminate termite colonies, when and where termites are present.
  • Less disruptive than liquid treatments to your home and lifestyle - no drilling, trenching or scheduling hassles.
  • Providing you with long-term protection and peace of mind.
  • The Sentricon Termite Elimination System earned the Presidential Green Chemistry Challenge award.

How is the Sentricon Termite Colony Elimination System Installed?

A professional technician will assess your property, install Sentricon stations around the home and then regularly monitor these Sentricon stations for the presence of termites. Once the attacking termite colony is eliminated service doesn't stop. We provide continued service and ongoing monitoring. The system acts like a termite alarm to protect the home from future termite attacks.

For more information visit

Our Story

"Treat others as you want to be treated.

Owner, Gene Schuessler, Advanced Pest Control Systems

Owner, Gene E. Schuessler saw a need for a quality pest control firm in the area. On September 1, 1980, he and his good friend and at that time partner, Jim Dodd, started Advanced Pest Control Systems, Inc. The next year Gene's son Gary returned to Cape Girardeau to attend SEMO University and joined the business.  Advanced Pest Control Systems is now in their 34th year of business and growing everyday. Currently, there are 20 field technicians and an office staff of four.  Advanced Pest Control Systems is still very much family run. Gene's son, Gary Schuessler, daughter, Deanna Niederkorn, and wife, Dorothy all are active in the business. 

Gene has more than 50 years of experience in the pest control industry and he keeps up with the latest in pest control improvement. Advanced Pest Control Systems, Inc. has been a member of the Chamber of Commerce and has been a 30-year member of both the National Pest Control Association, the Missouri Pest Control Association and a member of the Greater St. Louis Pest Control Association. Gene was also presented with the 2012 Dr. Wilbur Enns Man of the Year award by Missouri Pest Management Association.The award is given in recognition of a person who has been outstanding in their contribution of time, talent and innovation causing a positive result in the betterment of the Association and its' membership. Advanced Pest Control Systems believes their continued growth is due to the emphasis on effective service with a watchful eye to the customer's property and safety. When asked his motto, Gene will reply succinctly, "Treat others as you want to be treated.”

Bug Library

Our job is to help control pest problems you might have. Our Bug Library helps you understand what bugs and pests are the most common in our area and the different categories we service. Our services are not limited to these specific pests.

Community Involvement


Local Organizations

  • SEMO District Fair
  • Special Olympics
  • Area School Sports Programs
  • Cape Girardeau Chamber of Commerce 
  • Cape Noon Optimist Club
  • Cape Rotary Club
  • BNI of Cape and Jackson
  • United Way
  • Habitat for Humanity
  • Parks and Recreation Spaghetti Day

National Organizations

  • St. Louis Pest Management Association
  • National Pest Management Association
  • Missouri Pest Management Association – Gary has been the Vice President of Region #5 for four years.
  • American Heart Association 
  • St. Judes Children's Hospital


  • 2012 Missouri Pest Management Association Man of the Year (Gene)
  • People's Choice Award 2009-2014
  • Cape Noon Optimist Club

Contact Us

To request an appointment, please fill out the form below. In the request an appointment box please request a time, date and list the hours available.  Someone from our office will contact you to confirm request and set up your appointment.